Sunday, June 13, 2010

Chiropractic Treatment of Behavior Problems: When Is Evidence Not Evidence?

Today on my ADHD blog I posted information about the use of chiropratic with children who have behaviour problems. I'd like to repeat the information here because I think it applies to autism as well.

An excellent article/blog at Psychology Today.

Jean Mercer, PhD, blogs today on Psychology Today about a recent article claiming to prove that chiropractic treatment of children for behaviour problems works. Here is the actual article: (Alcantara, J., & Davis, J., The chiropractic care of children with Attention Deficit/Hyperactivity Disorder: A retrospective series) was published in 2010 in Explore: The Journal of Science and Healing (pp. 173-182).

The authors examined 4 cases from their records in which children and adolescents had received spinal manipulations and advice about dietary supplements from chiropractors over several months. (Note, these are not randomly chosen cases, just four cases picked out that worked out. ) They used a 15-item checklist of ADHD symptoms showed that the symptoms improved from the pre-treatment to the post-treatment period. From this very small amount evidence Alcantara and Davis concluded that the treatment was an effective way to alleviate ADHD. They attempt to prove something remarkable with just a hint of support.

There are some serious problems with not only the amount of this evidence, but with it's nature. First, to just pick four cases and make any assumption out of that data is, well, dangerous. You wouldn't use this method to prove any drug therapy worked! But with chiropractic, it's seems OK. (I mean, who will get hurt, besides your wallet?) This "evidence" is so prone to being affected by chance to use it is silly at best, and misleading at worse. Scientifically, before making these kinds of claims we need a large number of cases. Especially when there are so many different things that could affect the outcome. Mercer explains this really nicely with an analogy about picking four black socks out of a hugh pile of socks. The larger the pile, the less likely the first four are really telling you much about the pile. The next four in a row might be white, green or yellow! Probability studies tell any scientist NOT to do this.

Alcantara's study is also basically a "before and after" study. You follow someone who gets a certain treatment and compare how they were doing before the treatment and after the treatment. On it's face this sounds logical, but it's not. There are so many things that could have an effect. Age, time, parent's expectation, getting attention from the study itself, teachers and parents being relieved that after years of problems their child or student is now in a study and professionals are helping them! This is one of the dangers of this type of study, and one of the reasons you need a large sample of subjects to make sure these influences are't confounding your data. Four is not a large number, it's a number that increases the possibility for this kind of mistake.

There is no control group to compare these kids to. What if we took just four other students and did nothing, or had them take part in a sham study where the treatment might be made up? Would the results be any different? This is one way we avoid the problems of expectations and time and all the other things that can mislead us. But there is none of that, none. And this "study" is about a medical intervention for a serious life long disability!

There are also other problems with this study, it was not blinded properly, so people taking part knew what outcome was expected (scientific research has so clearly shown that not blinding these sorts of research studies causes problems with validity). And we don't know what other treatment interventions these children were involved with that might have had an effect on the outcome.

The problem here is that this study will be used by "holistic" treatment providers who will make claims to the public that there is a "published" and "peer reviewed" study that shows chiropractic manipulation is a helpful treatment for behavioural problems and ADHD in children.

THERE IS NO SUCH STUDY.

A much more in-depth analysis of the use of Chiropractic treatment on children can be found at Science Based Medicine. This article clearly shows that the use of chiropractic treatments is simply scientifically indefensible.

I suggest any parent thinking about using alternative medicine for behavioural problems read this article ....twice!

This week, in my practice, two more parents showed up who had been using "alternative medicine" with their children. Here in BC children below the age of 6 get nearly $20,000 to use for the treatment of their choice ...to a limit. Both had used all their monies on chiropractic, homeopathic and "auditory retraining" programs. None was left for basic interventions by a behavioural or speech specialist to teach communications skills or parenting techniques. These were sad situation. But when searching the internet for tretments what they found was a list of these "wholistic" practitioners offering everything from massage, diets, sound therapy to chelation therapy. None of which are supported by science. Again this week I went on line and found a local Naturopathic Physician (NP sometimes is referred to as "Not a Physician") offering" homeopathic vaccinations."

These parents were mislead by what they thought was legitimate research they found on the web. Research like the research above. One way to prevent this from happening to you is to use your medical doctor for advice, not a practitioner of holistic medicine! Look to web pages like Science-Based Medicine (which has a nice list of similar pages and resources) and I often send people to look up treatments on a very good skeptical site: Quackwatch.

When considering any treatment you can also simply try typing in the treatments name and words such as "skeptic."

Finally, because so many individuals are taking their children to homeopaths for unproven or disproven treatments, I'd like to suggest watching Richard Dawkin's video on homeopathy found here. It's an excellent place to start. And if you have a sense of humour (and watching people spend their money on these treatments you need a sense of humour, you could watch this funny video from Mitchell and Web.

For more information about scientifically validated interventions for children and adolescents with behaviour problems, ADHD, autism, Aspergers and related disorders please visit my web page at www.relatedminds.com or www.socialcognitivetherapy.com I have offices in Burnaby (serving New Westminster, Coquitlam, Port Moody and Maple Ridge) as well as offices in downtown Vancouver. I am a registered psychologist and registered marriage and family therapist, and would be more than happy to speak with you about possible treatments and interventions.

2 comments:

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  2. I get a lot of these posts they resort to name calling. And many that seem to be anti-intellectual. "Overly educated" is a bad thing. I was thinking, maybe I'll go to medical doctors who didn't finish medical school? What is the issue here? Why do people object to the opinions of others because the others are "educated?"

    And exactly how am I a pseudoscientist? What in my article is "pseudoscience?" You can't just change the meaning of words.

    As to why 250,000 American's die each year as the result of medical "malpractice" (very different than your statement referring to drugs/pharmaceutical related problems, I'll just quote SkeptDoc rather than rewriting this very misunderstood problem:

    Yes, it's true, but the number is a little off. http://articles.mercola.com/sites/articl… says it should be 225,000 (between unneccessary surgeries, medication errors in the hospital, other errors in the hospitals, etc).
    It specifies:
    "ALL THESE ARE DEATHS PER YEAR:
    * 12,000 -- unnecessary surgery
    * 7,000 -- medication errors in hospitals
    * 20,000 -- other errors in hospitals
    * 80,000 -- infections in hospitals
    * 106,000 -- non-error, negative effects of drugs
    These total to 225,000 deaths per year from iatrogenic causes!!"
    [edit]: The article also mentions the 44,000 to 98,000 deaths as a result of medical errors... that's included in the numbers above that I listed. It's not lies at all and it's fully verified by the AMA and JAMA (although they may list it in different ways so you sometimes have to read closer). It also points out that the U.S. is an average of 12th (out of 13) on a list for 16 available health indicators... the article as a whole is an interesting read that is cited so I'd read through the whole thing.

    So what does this have to do with chiropractic for behaviour problems? I don't know. Seems totally unrelated to me. And what does ringworm have to do with it? I'm not sure, there really isn't any connection except the writer's distaste for medicine, people who are educated, and the scientific method. Why all the name calling and anger?

    When I break my leg, I'm still going to the hospital. I'm seeing a doctor and not a homeopathic practitioner. I'm seeing a doctor for issues relating to health rather than seeing someone who practices a method that has no scientific backing, FAILED in numerous double blinded studies (do you understand, many of these treatments were shown NOT to work -NOT to work!) and when after several treatments of differing form are applied to a problem, over a period of weeks, I'm not going to jump to the conclusion that the one I support or was last in line was THE treatment that made all the difference. I guess that's because I'm educated in the scientific method. And I know that one of the most influential things on these kinds of illnesses is the passage of time. Even more powerful than most medications!

    The problem is we need to be able to figure out what works, and what doesn't, and yes, figure out what is just "dumb luck." And without real studies (and the double blind method is only one way we have to look at data) we can't tell. What we do know is that making an assumption based upon a single data point is very often a mistake. That is what we call "pseudoscience." Science would look at this, and try to replicate it. And I don't see any replications of the use of homeopathic medicine for ringwork in the literature.

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